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  1. Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. Four types of RNA modification writers (m6A, m1A, A-I editing, and APA) are widely involved in tumorigenesis and the TME...

    Authors: Wei Li, Ying Chen, Yao Zhang, Wen Wen and Yingying Lu
    Citation: BMC Immunology 2024 25:76
    Content type: Research Published on:

  3. In the current study, we evaluated whether atopic dermatitis (AD) affects the entire body rather than being limited to skin barrier damage and inflammation. We hypothesized that medium-term exposure of distant...

    Authors: Young-Won Kim, Eun-A Ko, Jehee Jang, Seohyun Jeong, Donghyeon Kim, Jung Soo Suh, Se-Yeon Lee, Inja Lim, Sung-Cherl Jung, Jung-Ha Kim, Tong Zhou, Hyoweon Bang and Jae-Hong Ko
    Citation: BMC Immunology 2024 25:74
    Content type: Research Published on:

  8. Porphyromonase gingivalis (P. gingivalis) is a type of bacteria that causes periodontitis, which is strongly correlated with systemic diseases such as diabetes. However, the effect of hyperglycemia on periodontit...

    Authors: Yuri Song, Jin-Ju Kwon, Hee Sam Na, Si Yeong Kim, Sang-Hun Shin and Jin Chung
    Citation: BMC Immunology 2024 25:69
    Content type: Research Published on:

  9. We previously demonstrated that the overall number of regulatory T (Treg) cells decrease proportionately with helper CD4+ T cells and their frequencies increase in antiretroviral therapy (ART)-naive human immunod...

    Authors: Ambada N. Georgia, Ntsama E. Claudine, Sake N. Carole, Ngu N. Loveline, Lissom Abel, Tchouangeu T. Flaurent, Sosso Martin, Alain Bopda Waffo, Malachy Okeke, Charles Esimone, Chae Gyu Park, Colizzi Vittorio, Etoa François-Xavier and Nchinda W. Godwin
    Citation: BMC Immunology 2024 25:68
    Content type: Research Published on:

  11. There is substantial evidence indicating that cytokines play a role in the immune defense against tuberculosis. This study aims to evaluate the levels of various cytokines in pleural effusion to ditinguish bet...

    Authors: Yuzhen Xu, Jing Wu, Qiuju Yao, Qianqian Liu, Huaxin Chen, Bingyan Zhang, Yuanyuan Liu, Sen Wang, Lingyun Shao, Wenhong Zhang, Qinfang Ou and Yan Gao
    Citation: BMC Immunology 2024 25:66
    Content type: Research Published on:

  12. Authors: Maimonah Alghanmi, Faisal Minshawi, Tarfa A. Altorki, Ayat Zawawi, Isra Alsaady, Abdallah Y. Naser, Hassan Alwafi, Soa’ad M. Alsulami, Ala A. Azhari, Anwar M. Hashem and Rowa Alhabbab
    Citation: BMC Immunology 2024 25:65
    Content type: Correction Published on:

    The original article was published in BMC Immunology 2024 25:21

  13. HIV has an effect on lowering CD4 cell count, which lowers the ability to resist contamination. For patients on ART in areas with limited resources, the CD4 cell count assessment is crucial for determining tre...

    Authors: Gebru Gebremeskel Gebrerufael and Zeytu Gashaw Asfaw
    Citation: BMC Immunology 2024 25:64
    Content type: Research Published on:

    The Correction to this article has been published in BMC Immunology 2024 25:79

  14. Carcinoembryonic-antigen-related cell-adhesion molecule 1 (CEACAM1) is an adhesion molecule that acts as a coinhibitory receptor in the immune system. We previously demonstrated that CEACAM1 is predominantly e...

    Authors: Haruki Matsumoto, Ryota Sudo, Yuya Fujita, Michio Onizawa, Kenji Saito, Yuya Sumichika, Shuhei Yoshida, Jumpei Temmoku, Naoki Matsuoka, Tomoyuki Asano, Shuzo Sato, Eiji Suzuki, Takeshi Machida and Kiyoshi Migita
    Citation: BMC Immunology 2024 25:63
    Content type: Research Published on:

  15. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complicated, heterogeneous condition distinguished by post-exertional neuroimmune exhaustion and multisystem symptoms. Its complexity poses chal...

    Authors: Jacob Batham, Jessica Dwyer, Natalie Eaton-Fitch and Sonya Marshall-Gradisnik
    Citation: BMC Immunology 2024 25:62
    Content type: Research Published on:

  16. Major Depressive Disorder, or depression, has been extensively linked to dysregulated HPA axis function, chronic inflammation and cardiovascular diseases. While the former two have been studied in depth, the m...

    Authors: Zachary Hage, Miguel M. Madeira, Dimitris Koliatsis and Stella E. Tsirka
    Citation: BMC Immunology 2024 25:61
    Content type: Review Published on:

  17. Immune checkpoint inhibitor rechallenge has emerged as a prominent study area in non-small cell lung cancer (NSCLC). β-glucan was reported to reverse resistance to anti-PD-1/PD-L1 inhibitors by regulating the ...

    Authors: Qian Geng, Yingying Lu, Dongqing Li, Lanqun Qin, Chunjian Qi, Xiaolin Pu, Yi Zhuang, Yajun Zhu, Quanbin Zha, Ge Wang and Hua Jiang
    Citation: BMC Immunology 2024 25:60
    Content type: Research Published on:

  18. To ascertain the connection between cuproptosis-related genes (CRGs) and the prognosis of hepatocellular carcinoma (HCC) via single-cell RNA sequencing (scRNA-seq) and RNA sequencing (RNA-seq) data, relevant d...

    Authors: Yong Wang, Fenglin Zang, Bing Shao, Yanan Gao, Haicui Yang, Yuhong Guo, Tingting Ding and Baocun Sun
    Citation: BMC Immunology 2024 25:59
    Content type: Research Published on:

  19. Systemic Lupus Erythematosus (SLE) has a strong genetic susceptibility, but little is known about the impact of diet on disease severity. The Western diet is typically deficient in magnesium (Mg), and given th...

    Authors: Alberto Verlato, Teresina Laragione, Sofia Bin, Randie H. Kim, Fadi Salem, Percio S. Gulko and Paolo Cravedi
    Citation: BMC Immunology 2024 25:58
    Content type: Research Published on:

    The Correction to this article has been published in BMC Immunology 2024 25:67

  20. Sepsis is a life-threatening condition triggered by uncontrolled immune responses to infection, leading to widespread inflammation, tissue damage, organ dysfunction, and potentially death. The liver plays a cr...

    Authors: Peiying Wang, Yiran Zheng, Jiaman Sun, Yumo Zhang, Wing Keung Chan, Yan Lu, Xiaohong Li, Zhouxin Yang and Youwei Wang
    Citation: BMC Immunology 2024 25:57
    Content type: Research Published on:

  21. Leukemia inhibitory factor (LIF) is a multifunctional member of the IL-6 cytokine family that activates downstream signaling pathways by binding to the heterodimer consisting of LIFR and gp130 on the cell surf...

    Authors: Shengyan Zhao, Han Deng, Ying Lu, Yiran Tao, David Li, Xiaohua Jiang, Xian Wei, Xiaofeng Chen, Fanxin Ma, Yuxi Wang, Lantu Gou and Jinliang Yang
    Citation: BMC Immunology 2024 25:56
    Content type: Research Published on:

  22. Retinol binding protein 4 (RBP4) is a mediator of inflammation and related to skin lesion formation, which suggests its engagement in psoriasis pathology and progression. This study intended to explore the cha...

    Authors: Runting Niu, Zhijia Li, Wanqing Jiang, Qingyan Yang, Xinfei Duan, Lixiao Sun, Zhijie Cheng, Junhui Huang, Lihong Li, Junge Ma, Taiping Hu, Lijuan Zhou, Juan Du, Chang Wang and Feifei Liu
    Citation: BMC Immunology 2024 25:55
    Content type: Research Published on:

  23. HIV-exposed uninfected infants (HEU) appear more vulnerable to infections compared to their HIV-unexposed uninfected (HUU) peers, generally attributed to poor passive immunity acquired from the mother. This ma...

    Authors: Luc-Aimé Kagoué Simeni, Gabriel Loni Ekali, Clauvis Kunkeng Yengo, Rodrigue Kamga Wouambo, Janett Fischer, Oumarou M’rikam A. Bessong, Joseph Fokam, Louis-Marie Yindom and Jules Clément Assob Nguedia
    Citation: BMC Immunology 2024 25:54
    Content type: Research Published on:

  24. Primary Sjogren's syndrome (pSS) is a prevalent autoimmune disease. The immune dysregulation it causes often leads to the development of diffuse large B-cell lymphoma (DLBCL) in clinical practice. However, how...

    Authors: Yanan Xu, Jianxing Han, Ziyi Fan and Shufen Liang
    Citation: BMC Immunology 2024 25:53
    Content type: Research Published on:

  25. Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by hyperglycemia resulting from defects in insulin secretion and/or insulin action. Increasing evidence suggests that inflammation played a...

    Authors: Li Zhang, Yuanbin Li, Honglei Wang, Yirui Guo, Xiaotong Wang, Hongmei Wu, Qing Zhang, Li Liu, Ge Meng, Shunming Zhang, Shaomei Sun, Ming Zhou, Qiyu Jia, Kun Song, Anna Stubbendorff, Yeqing Gu…
    Citation: BMC Immunology 2024 25:52
    Content type: Research Published on:

  26. Glioblastoma is characterized by high aggressiveness, frequent recurrence, and poor prognosis. Histone acetylation-associated genes have been implicated in its occurrence and development, yet their predictive ...

    Authors: Xingyi Jin, Zhigang Qin and Hang Zhao
    Citation: BMC Immunology 2024 25:51
    Content type: Research Published on:

  28. The systemic inflammatory syndrome called “cytokine storm” has been described in COVID-19 pathogenesis, contributing to disease severity. The analysis of cytokine and chemokine levels in the blood of 21 SARS-C...

    Authors: Estefanía Calvo-Alvarez, Sarah D’Alessandro, Nunzia Zanotta, Nicoletta Basilico, Silvia Parapini, Lucia Signorini, Federica Perego, Kevin Kamau Maina, Pasquale Ferrante, Annalisa Modenese, Pierluigi Pizzocri, Andrea Ronsivalle, Serena Delbue and Manola Comar
    Citation: BMC Immunology 2024 25:49
    Content type: Research Published on:

  29. TLR7 is a key player in the antiviral immunity. TLR7 signaling activates antigen-presenting cells including DCs and macrophages. This activation results in the adaptive immunity including T cells and B cells. ...

    Authors: Yosuke Ota, Ryosaku Inagaki, Yasuhiro Nagai, Yuko Hirose, Masashi Murata and Setsuko Yamamoto
    Citation: BMC Immunology 2024 25:48
    Content type: Research Published on:

  30. There is currently insufficient data regarding immune parameters and relationship with severity of malaria infection in Enugu, Nigeria where the economic and social costs of the disease and its management are ...

    Authors: Angela Ogechukwu Ugwu, Rebecca Chinyelu Chukwuanukwu, Friday Alfred Ehiaghe and Emmanuel Onyebuchi Ugwu
    Citation: BMC Immunology 2024 25:47
    Content type: Research Published on:

  31. The pathogenic microorganisms that cause intestinal diseases can significantly jeopardize people's health. Currently, there are no authorized treatments or vaccinations available to combat the germs responsibl...

    Authors: Saeed Mikaeel, Abbas Doosti and Ali Sharifzadeh
    Citation: BMC Immunology 2024 25:46
    Content type: Research Published on:

  32. Interstitial lung disease (ILD) is a prevalent complication in patients with common variable immunodeficiency (CVID) and is often related to other characteristics such as bronchiectasis and autoimmunity. Becau...

    Authors: Ghamartaj Khanbabaee, Fatemeh khazaii, Zahra Chavoshzadeh, Mahsa Rekabi, Zahra Ghomi, Vahide Zeinali, Matin Pourghasem, Maedeh Soflaee and Mahsa Ghadrdan
    Citation: BMC Immunology 2024 25:45
    Content type: Research Published on:

  33. Malaria is a life-threatening parasitic disease typically transmitted through the bite of an infected Anopheles mosquito. There is ample evidence showing the potential of malaria infection to affect the counts...

    Authors: Samuel Antwi-Baffour, Benjamin Tetteh Mensah, Simon Aglona Ahiakonu, Dorinda Naa Okailey Armah, Samira Ali-Mustapha and Lawrence Annison
    Citation: BMC Immunology 2024 25:44
    Content type: Research Published on:

  34. HIV has been reported to interfere with protective vaccination against multiple pathogens, usually through the decreased effectiveness of the antibody responses. We aimed to assess neutralizing antibody respon...

    Authors: Armel Landry Batchi-Bouyou, Jean Claude Djontu, Line Lobaloba Ingoba, Jiré Séphora Mougany, Freisnel Hermeland Mouzinga, Jacques Dollon Mbama Ntabi, Franck Yannis Kouikani, Arcel Christ Massamba Ndala, Steve Diafouka-kietela, Raoul Ampa and Francine Ntoumi
    Citation: BMC Immunology 2024 25:43
    Content type: Research Published on:

  35. Triple-Negative Breast Cancer (TNBC) is known for its aggressiveness and treatment challenges due to the absence of ER, PR, and HER2 receptors. Our work emphasizes the prognostic value of LCP1 (Lymphocyte cyto...

    Authors: Shuaikang Pan, Mengting Wan, Hongwei Jin, Ran Ning, Jinguo Zhang and Xinghua Han
    Citation: BMC Immunology 2024 25:42
    Content type: Research Published on:

  36. Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by disturbance of pro-inflammatory and anti-inflammatory lymphocytes. Growing evidence shown that gut microbiota participated in the oc...

    Authors: Fen-Ping Lian, Fen Zhang, Chun-Miao Zhao, Xu-Xia Wang, Yu-Jie Bu, Xing Cen, Gui-Fang Zhao, Sheng-Xiao Zhang and Jun-Wei Chen
    Citation: BMC Immunology 2024 25:41
    Content type: Research Published on:

  37. Psoriasis has a global prevalence of 1–3%, with variations observed across different ethnic groups and geographical areas. Disease susceptibility and response to anti-tumor necrosis factor-α (TNFα) drugs sugge...

    Authors: Fatma Z. Kamel, Heba Allah Mohamed Hoseiny, Aya A. El Shahawy, Ghada Boghdadi and Alia A. El Shahawy
    Citation: BMC Immunology 2024 25:40
    Content type: Research Published on:

  38. Previous observational studies have shown a bidirectional association between immune-mediated inflammatory disorders (IMID) and periodontal disease. However, evidence regarding the causal role of IMID and peri...

    Authors: Rui Zhang, Hairong Ma, Dan Wang and Hualin Zhang
    Citation: BMC Immunology 2024 25:39
    Content type: Research Published on:

  39. Variations in the innate and adaptive immune response systems are linked to variations in the severity of COVID-19. Natural killer cell (NK) function is regulated by sophisticated receptor system including Kil...

    Authors: Narges Karami, Shaghik Barani, Mona Fani, Seppo Meri, Reza Shafiei and Kurosh Kalantar
    Citation: BMC Immunology 2024 25:38
    Content type: Research Published on:

  40. Although immune checkpoint inhibitors (ICIs) have brought survival benefits to non-small cell lung cancer (NSCLC), disease progression still occurs, and there is no consensus on the treatment options for these...

    Authors: Kang Wang, Zhenxue Fu, Guanxing Sun, Yancui Ran, Nannan Lv, Enbo Wang and Huan Ding
    Citation: BMC Immunology 2024 25:37
    Content type: Research Published on:

  41. Rheumatoid arthritis (RA) is a chronic immune system disease with a high disability rate threatening the living quality of patients. Identifying potential biomarkers for RA is of necessity to improve the preve...

    Authors: Linxiao Ma, Huijie Liu, Ping Shao and Qian Lv
    Citation: BMC Immunology 2024 25:36
    Content type: Research Published on:

  42. For the past three years, the pandemic has had a major effect on global public health, mainly on those with underlying medical conditions, such as people living with Multiple Sclerosis. Vaccination among this ...

    Authors: Seyedeh Sadigheh Hamzavi, Rosemina Bahrololoom, Sepideh Saeb, Nahid Heydari Marandi, Marzieh Hosseini, Alimohammad Keshtvarz hesam abadi and Marzieh Jamalidoust
    Citation: BMC Immunology 2024 25:35
    Content type: Research Published on:

  43. Previous studies have reported the potential impact of immune cells on kidney stone disease (KSD), but definitive causal relationships have yet to be established. The purpose of this paper is to elucidate the ...

    Authors: Dongfeng Yuan, Junyi Yang, Weisong Wu, Yirixiatijiang Amier, Xianmiu Li, Wenlong Wan, Yisheng Huang, Jiabo Li and Xiao Yu
    Citation: BMC Immunology 2024 25:34
    Content type: Research Published on:

  46. Thyroid eye disease (TED) is an inflammatory process involving lymphocyte-mediated immune response and orbital tissue damage. The anti-insulin-like growth factor-1 receptor (IGF-1R) antibodies produced by B ly...

    Authors: Renyan Wang, Delu Song, Yong Zhong and Hui Li
    Citation: BMC Immunology 2024 25:31
    Content type: Research Published on:

  47. Immune-mediated necrotizing myopathy (IMNM) is an idiopathic inflammatory myopathy (IIM). Though patients with IMNM were not considered to show skin rash, several reports have showed atypical skin conditions i...

    Authors: Takashi Kurashige, Rie Nakamura, Tomomi Murao, Naoko Mine, Mayu Sato, Riho Katsumata, Yuhei Kanaya, Yoriko Dodo, Tomohito Sugiura and Tomohiko Ohshita
    Citation: BMC Immunology 2024 25:30
    Content type: Research Published on:

  48. Several PD-1 antibodies approved as anti-cancer therapies work by blocking the interaction of PD-1 with its ligand PD-L1, thus restoring anti-cancer T cell activities. These PD-1 antibodies lack inter-species ...

    Authors: Hae-Mi Kim, Kyoung-Jin Kim, Kwanghyun Lee, Myeong Jin Yoon, Jenny Choih, Tae-Joon Hong, Eun Ji Cho, Hak-Jun Jung, Jayoung Kim, Ji Soo Park, Hye Young Na, Yong-Seok Heo, Chae Gyu Park, Heungrok Park, Sungho Han and Donggoo Bae
    Citation: BMC Immunology 2024 25:29
    Content type: Research Published on:

  49. Metronomic capecitabine used as an adjuvant therapy improves survival in patients with locoregionally advanced nasopharyngeal carcinoma (LA-NPC). This therapeutic approach may also contribute to improving immu...

    Authors: Qianyong He, Xiuling Luo, Lina Liu, Chaofen Zhao, Zhuoling Li and Feng Jin
    Citation: BMC Immunology 2024 25:28
    Content type: Research Published on:

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BMC Immunology

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