Fig. 6
From: The amelioration effect of sesamoside on inflammatory response in septic shock
Mice were intraperitoneally injected with LPS for 12 h, followed by DEX or sesamoside with a concentration gradient for 6 h. (A) The mRNA transcription of TNF-α, IL-6, IL-1β, and iNOS were determined by qPCR. (B) The protein expression of P-ERK, ERK, P-JNK, JNK, and NLRP3 was detected by western blots. (C) The statistical analysis of (B). (D) Representative morphological images by IHC staining (200x) were presented to assess the expression of P65. (E) The quantitative values of P65 in IHC. #P < 0.05 and ###P < 0.001 vs. control group, NS, not significant. *P < 0.05, **P < 0.01 and ***P < 0.001 vs. model group, NS, not significant