Fig. 2

(A) Raw264.7 cells were stimulated with 1 µg/mL LPS for 12 h, then treated with 1 µM DEX or 25, 50, 100, or 200 µM sesamoside for 6 h, the mRNA transcription of TNF-α, IL-6, IL-1β, and iNOS were determined by qPCR. (B) Raw264.7 cells were stimulated with 1 µg/mL LPS for 12 h, then treated with 1 µM DEX or 200 µM sesamoside for 6-, 12-, and 24 h, the mRNA transcription of TNF-α, IL-6, IL-1β, and iNOS were determined by qPCR. (C) The cell supernatants of (B) were collected, and NO production was measured. ^###P < 0.001 vs. control group. ^*P < 0.05, ^**P < 0.01 and ^***P < 0.001 vs. model group, NS, not significant