Table 5 All-positive for four algorithms for cyclosporine and tacrolimus renal impairment
PT | Cyclosporine | Tacrolimus | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
N | ROR(95%Cl) | PRR(χ2) | EBGM(EBGM05) | IC(IC025) | N | ROR(95%Cl) | PRR(χ2) | EBGM(EBGM05) | IC(IC025) | |
Renal impairment | 1091 | 5.14 (4.84–5.46) | 5.12 (3563.45) | 5.05 (4.81) | 2.34 (2.25) | 1283 | 5.22 (4.94–5.52) | 5.19 (4271.55) | 5.12 (4.89) | 2.36 (2.27) |
Blood creatinine increased | 1113 | 6.47 (6.09–6.86) | 6.43 (5013.36) | 6.33 (6.02) | 2.66 (2.57) | 1150 | 5.75 (5.42–6.1) | 5.72 (4398.77) | 5.63 (5.36) | 2.49 (2.41) |
Oliguria | 106 | 6.48 (5.35–7.85) | 6.48 (481.67) | 6.37 (5.43) | 2.67 (2.39) | 85 | 4.45 (3.6–5.52) | 4.45 (224.16) | 4.4 (3.68) | 2.14 (1.82) |
Peritoneal dialysis | 17 | 7.47 (4.62–12.08) | 7.47 (93.16) | 7.33 (4.9) | 2.87 (2.19) | 10 | 3.75 (2.01–6.99) | 3.75 (19.88) | 3.71 (2.2) | 1.89 (1.02) |
Dialysis | 95 | 2.5 (2.04–3.06) | 2.5 (84.76) | 2.49 (2.1) | 1.31 (1.02) | 164 | 3.73 (3.2–4.36) | 3.73 (323.9) | 3.7 (3.25) | 1.89 (1.66) |
Continuous haemodiafiltration | 12 | 4.39 (2.48–7.76) | 4.39 (31.01) | 4.35 (2.7) | 2.12 (1.31) | 28 | 8.97 (6.16–13.07) | 8.97 (192.36) | 8.73 (6.37) | 3.13 (2.58) |
Proteinuria | 345 | 7.35 (6.61–8.18) | 7.34 (1848.72) | 7.2 (6.59) | 2.85 (2.69) | 297 | 5.43 (4.84–6.09) | 5.42 (1051.2) | 5.34 (4.85) | 2.42 (2.25) |
Nephropathy toxic | 585 | 22.6 (20.78–24.58) | 22.52 (11277.97) | 21.17 (19.74) | 4.4 (4.28) | 572 | 18.98 (17.44–20.66) | 18.92 (9116.67) | 17.82 (16.6) | 4.16 (4.03) |
Renal tubular necrosis | 118 | 4.61 (3.84–5.53) | 4.61 (328.87) | 4.56 (3.92) | 2.19 (1.92) | 317 | 10.92 (9.76–12.22) | 10.9 (2748.98) | 10.55 (9.6) | 3.4 (3.23) |
Tubulointerstitial nephritis | 123 | 2.56 (2.14–3.05) | 2.56 (115.66) | 2.54 (2.19) | 1.35 (1.09) | 202 | 3.63 (3.16–4.17) | 3.63 (380.32) | 3.6 (3.2) | 1.85 1.64) |