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Table 3 Cox regression analysis of independent risk factors for 28-day mortality in patients with sepsis

From: LncRNA CYP1B1-AS1 as a clinical biomarker exacerbates sepsis inflammatory response via targeting miR- 18a- 5p

Parameters

HR

95%CI

P value

Lower

Higher

Age

2.01

0.798

5.061

0.139

Male

2.016

0.741

5.485

0.17

BMI

1.193

0.486

2.927

0.7

Smoke

1.922

0.855

4.324

0.114

Drink

1.014

0.39

2.638

0.976

Hypertension

1.474

0.582

3.735

0.413

Hyperlipidemia

1.806

0.662

4.93

0.248

Diabetes

1.785

0.752

4.237

0.189

Scr

2.63

0.856

8.083

0.091

Albumin

0.59

0.239

1.452

0.25

WBC

2.331

0.91

5.972

0.078

CRP

2.073

0.822

5.226

0.123

TNF-α

2.374

0.679

8.306

0.176

IL- 6

1.823

0.518

6.414

0.349

IL- 8

1.366

0.531

3.515

0.518

IL- 1β

2.365

0.757

7.382

0.138

APAHCE II score

2.923

1.029

8.303

0.044

SOFA score

3.868

1.066

14.033

0.040

CYP1B1-AS1

5.592

1.249

25.036

0.024

  1. BMI Body mass index, APACHE Acute physiology and chronic health evaluation, SOFA Sequential organ failure assessment, Scr Serum creatinine, WBC White blood cells, CRP C-reactive protein, PCT Procalcitonin, TNF-α Tumor necrosis factor-α, IL Interleukin