Skip to main content
Fig. 3 | BMC Immunology

Fig. 3

From: LncRNA CYP1B1-AS1 as a clinical biomarker exacerbates sepsis inflammatory response via targeting miR- 18a- 5p

Fig. 3

Silencing CYP1B1-AS1 mitigates LPS-induced effects on THP- 1 cell proliferation, apoptosis, and inflammation. A Impact of LPS concentrations on CYP1B1-AS1 levels in THP- 1 cells after 48 h. B Impact of LPS induction (1 µg/ml) on CYP1B1-AS1 levels in THP-1 cells. C RT-qPCR assessment of CYP1B1-AS1 siRNA transfection efficiency in THP- 1 cells. D RT-qPCR analysis of CYP1B1-AS1 expression in THP- 1 cells treated with LPS and si-CYP1B1-AS1. E-F. Flow cytometry and ELISA assay were used to assess cell apoptosis and inflammation factors in LPS and si-CYP1B1-AS1-treated cells. ** P < 0.01, *** P < 0.001, **** P < 0.0001

Back to article page

BMC Immunology

ISSN: 1471-2172

Contact us