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Fig. 4 | BMC Immunology

Fig. 4

From: Integrated bulk RNA sequencing and mass cytometry analysis reveal the circulating immune landscape in ischemic and hemorrhagic Moyamoya disease

Fig. 4

Overview of imaging mass cytometry on PBMCs in ischemic and hemorrhagic MMD patients. (A) Representative t-Distributed Stochastic Neighbor Embedding (t-SNE) plots of five PBMC clusters, including T cells, B cells, NK cells, monocytes, and DCs from MMD patients. (B) t-SNE heatmap of cluster markers. (C) Donut chart showing the proportions of PBMC subsets in ischemic and hemorrhagic MMD patients. (D) Bar chart comparing PBMC subset proportions between ischemic and hemorrhagic groups. (E) Heatmap showing protein expression levels across PBMC clusters. (F) Expression differences of CCR10 between ischemic and hemorrhagic groups in PBMC clusters. (G) Expression differences of CX3CR1 between ischemic and hemorrhagic groups in PBMC clusters. Significance: ns, p ≥ 0.05; *p < 0.05; **p < 0.01

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