Table 2 Comparison of symptoms, signs and involved organs between Group A (serum IgE ≤ 212 IU/mL) and Group B(serum IgE > 212 IU/mL)
From: Serum IgE in the clinical features and disease outcomes of anti-interferon-γ autoantibodies syndrome
Variables | Group A (n = 97) | Group B (n = 66) | P value |
|---|---|---|---|
Symptoms, n (%) | |||
Fever | 58(59.8) | 49(74.2) | 0.057 |
Chilly | 30(30.9) | 21(31.8) | 0.904 |
Cough | 83(85.6) | 53(80.3) | 0.373 |
Expectoration | 70(72.2) | 48(72.7) | 0.937 |
Hemoptysis | 10(10.6) | 6(3.1) | 1.000* |
Weight loss | 34(35.1) | 33(50.0) | 0.057 |
Fatigue | 28(28.9) | 35(53.0) | 0.001 |
Dyspnea | 25(25.8) | 36(54.5) | < 0.001 |
Loss of appetite | 26(26.8) | 30(45.5) | 0.014 |
Nausea | 5(5.2) | 6(9.1) | 0.355* |
Chest tightness | 15(15.5) | 16(24.2) | 0.222* |
Chest pain | 27(27.8) | 14(21.2) | 0.339 |
Bone or joint pain | 18(18.6) | 13(19.7) | 0.842* |
Headache | 20(20.6) | 12(18.2) | 0.841* |
Signs, n (%) | |||
Enlarged superficial lymph nodes | 62(63.9) | 54(81.8) | 0.013 |
Anemic appearance | 21(21.6) | 18(27.3) | 0.457 |
Moist rales | 13(13.4) | 21(31.8) | 0.005* |
Dry rales | 3(3.1) | 1(1.5) | 0.648* |
Pleural effusion | 6(6.2) | 5(7.6) | 0.758* |
Rash | 15(15.5) | 26(39.4) | 0.001 |
Skin abscesses | 9(9.3) | 7(10.6) | 0.794* |
Hepatomegaly | 2(2.1) | 12(18.2) | < 0.001* |
Splenomegaly | 3(3.1) | 9(13.6) | 0.015* |
Involved organs, n(%) | |||
Lung involvement | 94(96.9) | 62(93.9) | 0.442* |
Lymph nodes involvement | 83(85.6) | 61(92.4) | 0.181 |
Bone involvement | 50(51.5) | 31(47.0) | 0.566 |
Skin involvement | 25(25.8) | 30(45.5) | 0.009 |
Bone marrow | 2(2.1) | 7(10.6) | 0.032* |
Bloodstream infection | 14(14.4) | 15(22.7) | 0.212* |
Pleura | 14(14.4) | 10(15.2) | 1.000* |
Soft tissue | 6(6.2) | 6(9.1) | 0.549* |
Liver | 3(3.1) | 8(12.1) | 0.051* |
Spleen | 6(6.2) | 12(18.2) | 0.022* |