From: Serum IgE in the clinical features and disease outcomes of anti-interferon-γ autoantibodies syndrome
Variables | Group A (n = 97) | Group B (n = 66) | P value |
---|---|---|---|
General characteristics | |||
Gender, male n (%) | 51(52.6) | 40(60.6) | 0.405 |
Average age (years) | 54.99 ± 12.71 | 55.00 ± 12.30 | 0.717 |
BMI (kg/m2) | 21.48 ± 2.89 | 21.24 ± 3.21 | 0.542 |
Underlying diseases, yes n (%) | 48(49.5) | 27(40.9) | 0.366 |
Allergy disease, yes n (%) | 3(42.9) | 4(57.1) | 0.442* |
Residence, rural n (%) | 61(62.9) | 48(72.7) | 0.156 |
No. of infective pathogens | 4(2–5) | 5(3–7) | 0.010 |
Disseminated infection, yes n (%) | 84(86.6) | 60(90.9) | 0.294 |
Laboratory data | |||
AIGAs titers | 0.157 | ||
1: 100 n (%) | 11(11.3) | 8(12.1) | |
1: 500 n (%) | 26(26.8) | 7(10.6) | |
1: 2500 n (%) | 60(61.9) | 51(77.3) | |
WBC (x109cells/L) | 12.64(8.84–16.41) | 15.43(10.26–19.51) | 0.054 |
Neu (x109cells/L) | 9.20(5.33–13.09) | 11.10(7.08–16.14) | 0.059 |
Lym (x109cells/L) | 1.86 ± 0.99 | 1.87 ± 0.87 | 0.976 |
Eos (x109cells/L) | 0.26(0.11–0.57) | 0.41(0.13–1.04) | 0.094 |
Mon (x109cells/L) | 0.74(0.52–0.93) | 0.78(0.57–1.24) | 0.231 |
Hb (g/L) | 108.00 ± 21.13 | 93.54 ± 25.32 | 0.068 |
CRP (mg/L) | 83.54 ± 59.23 | 100.58 ± 67.69 | 0.100 |
ESR (mm/h) | 69.76 ± 30.77 | 85.00 ± 36.39 | 0.009 |
SF (μg/L) | 517.93(239.49–1063.64) | 855.96(441.01–1514.89) | 0.067 |
CD3+T cells (%) | 67.31(58.38–71.82) | 69.93(60.73–78.90) | 0.037 |
CD4+T cells (%) | 34.92 ± 10.06 | 36.84 ± 10.69 | 0.280 |
CD8+ T cells (%) | 27.39 ± 10.17 | 29.24 ± 9.25 | 0.261 |
NK cells (%) | 18.56 ± 8.36 | 15.65 ± 9.25 | 0.110 |
B cells (%) | 11.75(7.47–15.90) | 9.45(5.42–14.77) | 0.137 |
IgG (g/L) | 18.36(14.73–23.57) | 24.56(18.95–34.09) | < 0.001 |
IgA (g/L) | 1.13(0.70–1.61) | 2.85(2.08–3.62) | 0.021 |
IgM (g/L) | 1.07(0.72–1.55) | 2.39(1.66–3.02) | 0.889 |
IgG4 (g/L) | 1.29(0.51–2.19) | 1.53(0.92–2.97) | 0.101 |
GLB (g/L) | 39.60(35.02–45.85) | 44.75(37.35–52.97) | 0.009 |
ALB (g/L) | 32.75 ± 5.81 | 30.36 ± 6.75 | 0.035 |
CHE(U/L) | 5119.50(3662.00–7161.50) | 3767.00(2257.50–5986.00) | 0.002 |
D-Dimer(mg/L) | 442.00(235.00–902.00) | 695.00(270.00–1214.00) | 0.067 |