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Table 1 Comparison of demographic and laboratory data between Group A (serum IgE ≤ 212 IU/mL) and Group B (serum IgE > 212 IU/mL)

From: Serum IgE in the clinical features and disease outcomes of anti-interferon-γ autoantibodies syndrome

Variables

Group A (n = 97)

Group B (n = 66)

P value

General characteristics

 Gender, male n (%)

51(52.6)

40(60.6)

0.405

 Average age (years)

54.99 ± 12.71

55.00 ± 12.30

0.717

 BMI (kg/m2)

21.48 ± 2.89

21.24 ± 3.21

0.542

 Underlying diseases, yes n (%)

48(49.5)

27(40.9)

0.366

 Allergy disease, yes n (%)

3(42.9)

4(57.1)

0.442*

 Residence, rural n (%)

61(62.9)

48(72.7)

0.156

 No. of infective pathogens

4(2–5)

5(3–7)

0.010

 Disseminated infection, yes n (%)

84(86.6)

60(90.9)

0.294

Laboratory data

 AIGAs titers

  

0.157

 1: 100 n (%)

11(11.3)

8(12.1)

 

 1: 500 n (%)

26(26.8)

7(10.6)

 

 1: 2500 n (%)

60(61.9)

51(77.3)

 

 WBC (x109cells/L)

12.64(8.84–16.41)

15.43(10.26–19.51)

0.054

 Neu (x109cells/L)

9.20(5.33–13.09)

11.10(7.08–16.14)

0.059

 Lym (x109cells/L)

1.86 ± 0.99

1.87 ± 0.87

0.976

 Eos (x109cells/L)

0.26(0.11–0.57)

0.41(0.13–1.04)

0.094

 Mon (x109cells/L)

0.74(0.52–0.93)

0.78(0.57–1.24)

0.231

 Hb (g/L)

108.00 ± 21.13

93.54 ± 25.32

0.068

 CRP (mg/L)

83.54 ± 59.23

100.58 ± 67.69

0.100

 ESR (mm/h)

69.76 ± 30.77

85.00 ± 36.39

0.009

 SF (μg/L)

517.93(239.49–1063.64)

855.96(441.01–1514.89)

0.067

 CD3+T cells (%)

67.31(58.38–71.82)

69.93(60.73–78.90)

0.037

 CD4+T cells (%)

34.92 ± 10.06

36.84 ± 10.69

0.280

 CD8+ T cells (%)

27.39 ± 10.17

29.24 ± 9.25

0.261

 NK cells (%)

18.56 ± 8.36

15.65 ± 9.25

0.110

 B cells (%)

11.75(7.47–15.90)

9.45(5.42–14.77)

0.137

 IgG (g/L)

18.36(14.73–23.57)

24.56(18.95–34.09)

 < 0.001

 IgA (g/L)

1.13(0.70–1.61)

2.85(2.08–3.62)

0.021

 IgM (g/L)

1.07(0.72–1.55)

2.39(1.66–3.02)

0.889

 IgG4 (g/L)

1.29(0.51–2.19)

1.53(0.92–2.97)

0.101

 GLB (g/L)

39.60(35.02–45.85)

44.75(37.35–52.97)

0.009

 ALB (g/L)

32.75 ± 5.81

30.36 ± 6.75

0.035

 CHE(U/L)

5119.50(3662.00–7161.50)

3767.00(2257.50–5986.00)

0.002

 D-Dimer(mg/L)

442.00(235.00–902.00)

695.00(270.00–1214.00)

0.067

  1. *Fisher’s exact test