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Fig. 1 | BMC Immunology

Fig. 1

From: Combining machine learning with external validation to explore necroptosis and immune response in moyamoya disease

Fig. 1

The extraction of DE-NiNRGs and functional enrichment analysis. A: STA sample acquisition method. MMD: moyamoya disease. STA: superficial temporal artery. MCA: middle cerebral artery. HC: healthy control, non-MMD patients. B: PCA plots of training set (GSE189993) data after batch correction. Blue: Control samples. Yellow: MMD samples. C: Volcano plot of differentially expressed genes (DEGs) in the MMD training dataset. Red: upregulated genes, Blue: downregulated genes. D: Venn map of DEGs and necroinflammation and necroptosis related genes (NiNRGs). Green: DEGs of GSE189993. Blue: NiNRGs. Intersection: DE-NiNRGs. E: Bubble chart of GO-BP enrichment result with top 10 significance level. BP: Biological Process. F: Bubble chart of GO-CC enrichment result with top 10 significance level. CC: Cellular Component

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BMC Immunology

ISSN: 1471-2172

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