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Table 2 Clinical and morbidity data for children stratified by HIV and ART exposure status at 5 years

From: Phenotypic characterization of NK cells in 5-year-old children exposed to maternal HIV and antiretroviral therapy in early-life

Characteristic

Median (IQR)

[N(%)]

HEU

(N = 81)

HUU

(N = 52)

P value^

P value#

HEU MT (N = 38)

HEU LT

(N = 43)

Children’s age at sample collection (years)

5.0 (4.6–5.2)

5.2 (4.8-6.0)

5.2 (4.7-6.0)

0.086

0.139

Clinical factors

 

Weight (kg)

17.7 (16.0-19.7)

17.9 (15.7–20.0)

17.7 (16.0-19.2)

0.822

0.585

MUAC (cm)

16.0 (15.4–17.0)

16.4 (15.5–17.0)

16.0 (15.5–17.0)

0.798

0.772

HB(g/dL)

13.5 (12.5–14.5)

13.4 (12.7–14.2)

13.4 (12.7–14.1)

0.668

0.403

WBC (109 /L)

7.0 (5.5–8.9)

6.2 (5.2–7.1)

6.9 (5.7–8.6)

0.120

0.385

Morbidity

 

Sick clinic visits at ≤ 6 weeks of age

1.0 (1.0–1.0)

1.0 (1.0–1.0)

1.0 (1.0–1.0)

0.549

0.273

Sick clinic visits at > 6 weeks-6months

1.0 (1.0–1.0)

1.0 (1.0–1.0)

1.0 (1.0–1.0)

0.855

0.601

Sick clinic visits at > 6 months-12months

1.0 (1.0–2.0)

1.0 (1.0-1.3)

1.0 (1.0–1.0)

0.596

0.399

Sick clinic visits beyond 12 months

1.0 (1.0–2.0)

1.0 (1.0–2.0)

1.0 (1.0–2.0)

0.974

0.865

Combined sick clinic visit (birth- 5 years)

2.0 (1.0–3.0)

2.0 (1.0–3.0)

2.0 (1.0–3.0)

0.398

0.222

Hospitalization

 

 Yes

3 (7.9)

4 (9.3)

6 (11.5)

0.875

0.560

 No

35 (92.1)

39 (90.7)

46 (88.5)

  1. ^- p values for comparisons between HEULT, HEUMT and HUU, #- p values for comparisons between HEU and HUU. Abbreviations: cm- centimetres, dL- decilitre, HB- haemoglobin, HEU- HIV-exposed uninfected, HUU- HIV-unexposed uninfected, IQR- interquartile, kg- kilograms, L- litre, LT- long term, MT- medium term, MUAC- mid upper arm circumference, WBC- white blood cell count