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Table 1 Maternal factors during pregnancy and infant birth outcomes for children stratified by HIV and ART exposure status

From: Phenotypic characterization of NK cells in 5-year-old children exposed to maternal HIV and antiretroviral therapy in early-life

Characteristic

Median (IQR)

[N(%)]

HEU

(N = 81)

HUU

(N = 52)

P value^

P value#

HEU MT (N = 38)

HEU LT

(N = 43)

Maternal factors

 

Age (years)

30.0 (24.0-35.5)

33.0 (29.0-35.5)

29.0 (25.0–34.0)

0.078

0.118

Viral load (n = 81)

 

 Suppressed

33 (86.8)

39 (95.1)

N/A

0.247

N/A

 Unsuppressed

5 (13.2)

2 (4.9)

(missing = 2)

CD4 count (n = 81)

347 (230–589)

422 (308–535)

N/A

0.384

N/A

Birth outcomes

 

Gestational age at birth (weeks)

 

 Preterm (< 37)

2 (5.7)

8 (19.0)

2 (3.9)

0.050

0.126

 Term (≥ 37)

33 (94.3)

(missing = 3)

34 (81.0)

(missing = 1)

50 (96.1)

Birth weight(grams)

     

 <2500

6 (15.8)

4 (9.3)

3 (5.8)

0.304

0.369

 ≥2500

32 (84.2)

39 (90.7)

49 (94.2)

Sex

     

 Female

19 (50.0)

23 (53.5)

23 (44.2)

0.726

0.721

 Male

19 (50.0)

20 (46.5)

29 (55.8)

  1. ^- p values for comparisons between HEULT, HEUMT and HUU, #- p values for comparisons between HEU and HUU. Abbreviations: HEU- HIV-exposed uninfected, HUU- HIV-unexposed uninfected, IQR- interquartile, LT- long term, MT- medium term