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Fig. 3 | BMC Immunology

Fig. 3

From: From bioinformatics to clinical applications: a novel prognostic model of cuproptosis-related genes based on single-cell RNA sequencing data in hepatocellular carcinoma

Fig. 3

The determination of differentially expressed gene (DEG)-related CRGs. (a) Volcano map of DEG1 expression in the single-cell sequencing dataset. (b) Expression of CDKN2A in the single-cell sequencing dataset. (c) Scores of CRGs in 7 cell subsets. (d) Selection of the optimal threshold. (e) UMAP diagram showing high- and low-CRG activity cells on the basis of the optimal threshold. (f) Volcano map of the expression of CRGs in the single-cell sequencing dataset. (g) Volcano map of DEG2 expression in the TCGA dataset. (h) Venn diagram of the intersection of DEGs1, CRGs, and DEGs2 in tumor and nontumor samples. p < 0.05

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BMC Immunology

ISSN: 1471-2172

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