Fig. 6
From: Sepsis induced dysfunction of liver type 1 innate lymphoid cells

Transcriptome analysis of NK cells and ILC1 after CLP. a: PCA analysis of gene expression data of spleen NK cells, liver NK cells, and liver ILC1s. b - d: The volcano diagrams illustrated the differentially expressed genes of liver NK cells (b), liver ILC1 (c), and spleen NK cells (d) between sham and CLP conditions. In each volcano plot, up-regulated genes in CLP samples are represented on the right, while down-regulated genes are shown on the left. Significant genes (|log2FC| ≥ 1, p-value < 0.05) were denoted by red dots. e: Heat maps for NK cells and ILC1 function relevant genes. The expression of Ncr1 was analyzed by flow cytometry. f - h: GSEA of the genes differentially expressed between sham and CLP mice. Gene sets significant changed in spleen NK cells (f), liver ILC1s (g), and liver NK cells (h)