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Fig. 5 | BMC Immunology

Fig. 5

From: TLR7 agonist, DSP-0509, with radiation combination therapy enhances anti-tumor activity and modulates T cell dependent immune activation

Fig. 5

Gene expression related to anti-tumor immunity was increased in the tumor treated with combined RT and DSP-0509. A. Study schedule used for tumor mRNA expression analysis in CT26 model mice treated with combined DSP-0509 and RT. B. Hierarchical clustering analysis of mRNA expression data in each treatment group. C. Number of differentially expressed genes are shown in the Venn diagram. Each value shows the number of genes with increased expression more than 2 times in each treatment group compared to the control group. D. Expression levels of immune-related genes in each treatment group. n = 4–6 in each group. *False discovery rate (FDR)-adjusted P < 0.05 by the Student t-test

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BMC Immunology

ISSN: 1471-2172

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