Table 3 Laboratory findings of CVID patients with and without ILD
Parameters | Total (n = 60) | With ILD (n = 10) | Without ILD (n = 50) | P-value |
|---|---|---|---|---|
WBC × 103 (cell/uL), median (IQR) | 7.2 (5.1–9.4) | 11.0 (7.3–15.6) | 6.75 (9.1–4.65) | 0.013* |
Lymphocytes percent (%), median (IQR) | 30.2 (24.0-43.2) | 27.0 (22.5–38.5) | 30.85 (24.0–45.0) | 0.266 |
Neutrophils percent (%), median (IQR) | 59.6 (47.7–66.2) | 60.5 (54.0-66.25) | 59.15 (46.17–66.75) | 0.323 |
Hb (mg/dl), median (IQR) | 12.0 (10.3–13.6) | 10.9 (9.9–12.3) | 12.25 (10.35–13.67) | 0.243 |
Platelet × 103 (cell/uL), median (IQR) | 228.0 (154.25–324.5) | 337.0 (242.0-494.0) | 225.0 (136.5-279.5) | 0.011* |
CD3 + T cells %, median (IQR) | 78.0 (63.0–84.0) | 81.0 (76.0–83.0) | 76.9 (62.25–84.75) | 0.354 |
CD4 + T cells %, median (IQR)5 | 28.9 (21.0–37.0) | 32.1 (21.75–48.5) | 28.0 (20.0-35.5) | 0.570 |
CD8+ T cells %, median (IQR) | 36.5 (25.0–48.0) | 37.0 (20.048.2) | 36.25 (29.25-48.0) | 0.742 |
CD16+ B cells %, median (IQR) | 7.0 (5.4–12.0) | 14.5 (8.0-18.15) | 7.0 (5.3–11.0) | 0.078 |
CD19+ B cells %, median (IQR) | 7.7 (1.0-14.9) | 3.6 (1.0–10.0) | 8.0 (1.0–17.0) | 0.231 |
IgG (mg/dL), median (IQR) | 581.0 (165.25–798.5) | 220.0 (96.75–419.5) | 643.5 (193.75-839.25) | 0.084 |
IgA (mg/dL), median (IQR) | 22.0 (9.0-69.5) | 16.0 (3.5–34.0) | 26.5 (10.0-71.75) | 0.163 |
IgM (mg/dL), median (IQR) | 34.0 (17.0–68.0) | 13.0 (5.0-42.5) | 38.5 (19.0-73.25) | 0.055 |
IgE (mg/dL), median (IQR) | 2.8 (1.0–10.0) | 1.0 (8.5–0.7) | 4.0 (1.0-11.25) | 0.386 |