Table 2 Clinical features of CVID patients with and without ILD
Parameters | Total (n = 60) | With ILD (n = 10) | Without ILD (n = 50) | P-value |
|---|---|---|---|---|
Respiratory Manifestations | ||||
Cough, n (%) | 33 (55.0) | 6 (60) | 27 (54) | 0.503 |
Pneumonia, n (%) | 28 (45.9) | 10(100) | 18 (36) | 0.002* |
Sinusitis, n (%) | 20 (33.3) | 5 (50) | 15 (30) | 0.194 |
Otitis media, n (%) | 17 (28.3) | 4 (40) | 13 (26) | 0.295 |
Breath shortness, n (%) | 10 (16.7) | 1 (10) | 9 (18) | 0.468 |
Wheezing (n = 60) (%) | 7 (11.7) | 1 (10) | 6 (12) | 0.670 |
Bronchiectasis, n (%) | 4 (6.7) | 0 (0) | 4 (8) | 0.472 |
Gastrointestinal Manifestations | ||||
Diarrhea, n (%) | 22 (36.7) | 7 (70) | 15 (30) | 0.022* |
Other Manifestations | ||||
Dermatologic disorders, n (%) | 26 (43.3) | 4 (40) | 22 (44) | 0.550 |
Autoimmunity, n (%) Immune cytopenia | 17 (28.3) 10 (16.6) | 3 (30) 2 (20) | 14 (28) 8 ( 16) | 0.586 |
FTT, n (%) | 12 (20.0) | 0 (0) | 12 (24) | 0.087 |
PND, n (%) | 13 (21.7) | 4 (40) | 9 (18) | 0.132 |
Splenomegaly, n (%) | 13 (21.7) | 4 (40) | 9 (18) | 0.132 |
Oral candidiasis, n (%) | 10 (16.7) | 1 (10) | 9 (18) | 0.469 |
Clubbing, n (%) | 10 (16.7) | 2 (20) | 8 (16) | 0.531 |
Fever, n (%) | 9 (15.0) | 1 (10) | 8 (16) | 0.533 |
Hepatomegaly, n (%) | 5 (8.3) | 3 (30) | 2 (4) | 0.029* |
Abscess formation, n (%) | 4 (6.7) | 2 (20) | 2 (4) | 0.126 |
Cold, n (%) | 3 (5.0) | 1 (10) | 2 (4) | 0.427 |
Malignancy, n (%) | 3 (5.0) | 0 (0) | 3 (6) | 0.729 |