Table 2 Comparing the carrier frequency of KIR genes in the groups with severe or mild disease
KIR gene | severe disease N = 198 | mild disease n = 196 | severe vs. mild disease | |
|---|---|---|---|---|
N %F | N %F | p-value OR (95% CI) | ||
A haplotype associated genes | 2DL1 | 195 98.5% | 194 99.0% | NS |
2DL3 | 183 92.4% | 160 81.6% | 0.001* 1.132 1.048–1.223 | |
3DL1 | 192 97% | 182 92.9% | NS | |
2DS4 | 189 95.5% | 186 94.9% | NS | |
2DS4 fl. | 7 3.5% | 12 6.1% | NS | |
2DS4 del | 144 72.7% | 123 62.8% | 0.03* 1.58 1.032–2.429 | |
2DS4 fl/del | 38 19.2% | 51 26% | NS | |
B haplotype associated genes | 2DS1 | 65 32.8% | 92 46.9% | 0.004* 0.553 0.366–0.831 |
2DS2 | 107 54% | 129 65.8% | 0.017* 0.611 0.406–0.917 | |
2DS3 | 85 42.9% | 97 49.5% | NS | |
2DS5 | 48 24.2% | 54 27.6% | NS | |
3DS1 | 77 38.9% | 59 30.1% | NS | |
2DL2 | 131 66.2% | 120 61.2% | NS | |
2DL5 | 106 53.5% | 119 60.7% | NS | |