Fig. 4
From: miR-486-5p predicted adverse outcomes of SCAP and regulated K. pneumonia infection via FOXO1

The direct target genes of miR-486-5p were predicted from TargetScan, ECORI, miRDB, and miRWalk databases (a). K. pneumonia induced increasing miR-486-5p (b) and decreasing FOXO1 (c) in ACEII cells. miR-486-5p could negatively regulate the expression (c) and luciferase activity (d) of FOXO1 in K. pneumonia-treated ACEII cells. nsP > 0.05, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001