Potential role of IGF-1R in the interaction between orbital fibroblasts and B lymphocytes: an implication for B lymphocyte depletion in the active inflammatory phase of thyroid-associated ophthalmopathy

Table 2 Ophthalmology examination/evaluation of TED in the 15 patients

Examination/evaluation	Signs/grade	Eyes
Proptosis	Yes	15
Diplopia	Yes	12
Eyelids	Edema	11
Visual acuity	Decreased	15
Conjunctiva	Congestion	15
Conjunctiva	Edema	12
Cornea	Punctate infiltration	4
Cornea	Ulcer	8
Elevated intraocular pressure	Mild	4
	Moderate	6
	Severe	5
Ptosis	Yes	12
Upper eyelid retraction (mm)	< 2	1
	2 ~ 4	2
	> 4	12
Lower eyelid retraction (mm)	< 2	4
Lower eyelid retraction (mm)	2 ~ 4	2
Extraocular muscle motility	Partly limited	8
Extraocular muscle motility	Fixed	4
CAS	3–7 (4.83 ± 1.7)	15
NOSPECS	5	7
NOSPECS	6	8
EUGOGO	Very severe	15

CAS, clinical activity score; NOSPECS, no signs or symptoms, only signs, soft tissue involvement, proptosis, extraocular muscle involvement, corneal involvement, sight loss; EUGOGO, European group on Graves’ orbitopathy

ISSN: 1471-2172