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Fig. 5 | BMC Immunology

Fig. 5

From: Potential role of IGF-1R in the interaction between orbital fibroblasts and B lymphocytes: an implication for B lymphocyte depletion in the active inflammatory phase of thyroid-associated ophthalmopathy

Fig. 5

Interleukin-6 (IL-6) and regulated upon activation normal T cell expressed and secreted factors (RANTES) expression levels after 72 h of co-culturing four groups. (A) Rapid increase of IL-6 levels in four groups within 24 h, with significantly higher values for the T + T group at each detection time point than those of the other three groups. (B) Increased expression of RANTES within 24 h of co-cultivation in all groups, with the highest concentration of RANTES occurring in the T + T group 24 h after co-culture. Data are represented as the mean and standard deviation of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001

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