Fig. 3

Morphologies of orbital fibroblasts and B lymphocytes co-cultured for 72 h under a phase-contrast light microscope. (A) Co-culture model of TED patients (T + T group, both samples obtained from TED patients). (B) Co-culture model of B lymphocytes in TED patients and orbital fibroblasts in controls (T + N group, B lymphocytes sampled from TED patients and orbital fibroblasts sampled from control patients). (C) Co-culture model of B lymphocytes in controls and orbital fibroblasts in TED patients (N + T group, B lymphocytes sampled from control patients and orbital fibroblasts sampled from TED patients). (D) Co-culture model of B lymphocytes and orbital fibroblasts in controls (N + N group, both samples obtained from control patients)