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Fig. 3 | BMC Immunology

Fig. 3

From: Dominant negative biologics normalise the tumour necrosis factor (TNF-α) induced angiogenesis which exploits the Mycobacterium tuberculosis dissemination

Fig. 3

Graph showing the data obtained from 5 animals per group. All data in each figure is from one biological repeat. CFU counts at an 8th -week time point in guinea pig lung tissue. The graph shows a significant decrease in CFU count in treated groups. Twenty-one days of drug therapy with Xpro-1595 showed reduced viable bacilli in the lungs and spleen. Dissemination of bacilli was less in the spleen in Xpro-1595 treated guinea pigs when compared with M.tb infected guinea pigs without treatment (p < 0.001). Standard deviation was > 0.1

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BMC Immunology

ISSN: 1471-2172

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