Fig. 4
From: Bcl-3 regulates T cell function through energy metabolism

Bcl-3 deficiency inhibits ROS production and promote the necrosis and IFN-γ production of cells with stimulated by CD3/CD28. Jurkat and Bcl-3−/− Jurkat cells were activated with anti-CD3/CD28 for 24 h. (A) The intracellular ROS levels were stained using the ROS assay kit and determined by flow cytometry. (B) Cell apoptosis (B) and IFN-γ production (C)were determined by flow cytometry