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Fig. 4 | BMC Immunology

Fig. 4

From: Optimizing tumor-associated antigen-stimulated autologous dendritic cell and cytokine-induced killer cell coculture to enhance cytotoxicity for cancer immunotherapy in manufacturing

Fig. 4

Comparison of cell marker expression and cytotoxicity

(a) Comparison of cytokine-induced killer (CIK) cell marker expression on the 9th and 14th day between cytokine-stimulated dendritic cell (DC)- CIK cell coculture different DC: CIK cell ratios and the CIK cells-only control. (b) Comparison of cytotoxicity between cytokine-stimulated DC- CIK cell coculture and the control (CIK alone) at different CIK: K562 cell ratios on the 9th and 14th day. * indicates p-value < 0.05 compared with the control on the Student t-test. (c) We compared the cell numbers and viability between the antigen with cytokine co-stimulated DC-CIK group and the control group at different ratios of DC:CIK on the 9th and 14th days

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