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Fig. 2 | BMC Immunology

Fig. 2

From: Optimizing tumor-associated antigen-stimulated autologous dendritic cell and cytokine-induced killer cell coculture to enhance cytotoxicity for cancer immunotherapy in manufacturing

Fig. 2

Mature dendritic cells (mDCs) are characterized by marker expression and IL-12 production. (a) Quantitative analysis of antigen-presenting cell activation markers. The DC gating of mDCs was slightly lower than that of immature dendritic cells (iDCs). The expression of HLA-DR, CD86, and CD40 markers in iDCs and mDCs is similar. The expression of CD83 and (b) CCR7 markers in mDCs was higher than that in iDCs, and the expression of the CD14 marker in mDCs was significantly decreased. (c) The amount of IL-12 measured at the end of DC maturation showed an increase in production capacity. ** indicates p < 0.01. The results were repeated over three independent experiments in each case

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BMC Immunology

ISSN: 1471-2172

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