Table 2 Absolute counts and proportion of lymphocyte and CD4 + T cells in the peripheral blood in pSS and HCs
All pSS patients N = 79 | HCs N = 33 | p-value | |
|---|---|---|---|
Numbers of lymphocytes (cells/µl) | |||
Total T cells | 1047.98(730.89–1337.00) | 1210.71(980.78-1337.47) | 0.019 * |
Total B cells | 184.23(113.77-280.75) | 175.81(127.66-235.72) | 0.957 |
NK cells | 120.51(80.68-176.55) | 155.94(135.43-190.36) | 0.004 ** |
CD4 + T cells | 597.40(423.80-786.28) | 647.50(550.17-712.18) | 0.297 |
CD8 + T cells | 440.23(297.62-572.06) | 460.22(390.55-562.77) | 0.123 |
Th1 cells | 106.43(63.65-165.19) | 133.95(55.71-176.68) | 0.581 |
Th2 cells | 6.07(4.11–7.87) | 7.04(4.73–9.28) | 0.209 |
Th17 cells | 6.91(4.54–11.43) | 5.68(3.67–8.27) | 0.049 * |
Treg cells | 19.10(12.91–26.50) | 23.04(19.38–28.20) | 0.007 ** |
Proportions of lymphocytes (%) | |||
Total T cells | 73.04(66.75–81.19) | 74.23(73.49–80.96) | 0.365 |
Total B cells | 13.60(9.27–19.92) | 10.96(8.23–14.04) | 0.091 |
NK cells | 8.75(6.16–11.84) | 11.05(8.71–12.55) | 0.018 * |
CD4 + T cells | 39.50(33.64–46.93) | 39.78(36.03–44.59) | 0.906 |
CD8 + T cells | 31.16(24.63–39.65) | 29.78(26.13–36.20) | 0.786 |
Th1 cells | 19.73(13.08–27.27) | 19.51(12.24–25.58) | 0.594 |
Th2 cells | 1.12(0.78–1.53) | 1.24(0.86–1.48) | 0.934 |
Th17 cells | 1.41(0.80–2.24) | 0.89(0.62–1.25) | < 0.001*** |
Treg cells | 3.66(2.82–4.62) | 4.05(2.93–4.64) | 0.174 |
CD4 + T/CD8 + T | 1.35(0.91–1.90) | 1.38(0.91–1.56) | 0.542 |
Th1/Th2 | 17.08(10.69–25.70) | 15.84(9.52–19.03) | 0.473 |
Th17/Treg | 0.41(0.23–0.68) | 0.24(0.14–0.31) | 0.001 ** |
Th1/Treg | 5.73(3.30–8.54) | 5.67(3.27–7.98) | 0.461 |
Th2/Treg | 0.31(0.22–0.44) | 0.36(0.27–0.60) | 0.449 |