Fig. 1
From: Gentamicin promoted the production of CD4+CD25+ Tregs via the STAT5 signaling pathway in mice sepsis
GNT improved survival and reduced tissue inflammatory responses in LPS-induced neonatal sepsis. a GNT increased the survival outcome in LPS-induced neonatal sepsis. The survival was monitored for up to 7 days. b Tissues from each group were processed for histopathological examination. Newborn mice treated with LPS were highly susceptible to inflammation, neutrophil infiltration, and tissue injury in the lungs, liver, kidneys, and intestines. GNT attenuated these changes in the LPS group. c The degree of lung, liver, kidney, and intestine damage was determined using lung, liver, kidney, and intestine injury scoring. Data are expressed as mean ± SD, n = 10. *P < 0.05 versus control group; #P < 0.05 versus LPS group