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Fig. 5 | BMC Immunology

Fig. 5

From: The impact of HIV infection on the frequencies, function, spatial localization and heterogeneity of T follicular regulatory cells (TFRs) within human lymph nodes

Fig. 5

Epigenomic definition of TFRs and TFH cells. A Experimental design for ATAC-Seq and RNA-Seq experiments. B PCA plot of ATAC-Seq signal in TFRs and TFH cells. The top 10% of ATAC-Seq peaks (merged between subsets) by variance were used to create the PCA plot. Differential accessibility of canonical TFRs and TFH genes C FOXP3 D IL-21 and novel genes E FRL3 F DPP4

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BMC Immunology

ISSN: 1471-2172

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