Fig. 3
From: Immune correlates of cardiovascular co-morbidity in HIV infected participants from South India
CD4 and CD8 T-cell immune activation between treatment naïve and ART-treated participants stratified by nadir CD4 T-cell counts in comparison to the uninfected control group. CD4 and CD8 T cell immune activation were analyzed by Flow cytometry based on the surface expression of HLA-DR and CD38 dual positive CD4 and CD8 T cells. A, DR+38+: CD4 T-cell activation; B, CD8+DR+38+: CD8 T-cell activation; group 1a: Untreated participants with nadir CD4 T-cell counts < 200 cells/mm3; group 1b: Untreated participants with nadir CD4 T-cell counts 200–350 cells/mm3; group 1c: Untreated participants with nadir CD4 T-cell counts > 350 cells/mm3; group 2a: On ART participants with nadir CD4 T-cell counts < 200 cells/mm3; group 2b: On ART participants with nadir CD4 T-cell counts 200–350 cells/mm3; group 2c: On ART patients with nadir CD4 T-cell counts > 350 cells/mm3. Lines with asterix (*) show the significant difference (p < 0.05) between indicated groups with *p < 0.05, **p < 0.01, and ***p < 0.001