Fig. 2
From: Exhausted phenotype of circulating CD8+ T cell subsets in hepatitis B virus carriers
CXCR5+CD8+ T cells exhibit a more suppressive phenotype than their CXCR5− counterparts in HBV carriers. A Flow cytometric detection of PD1, TIM3, LAG3, and CTLA4 on CXCR5+CD8+ T cells and CXCR5−CD8+ T cells in HBV carriers; B–E paired analysis of PD1, TIM3, LAG3, and CTLA4 expression on CXCR5+CD8+ T cells and CXCR5−CD8+ T cells in HBV carriers; F–G differential expression of PD1, TIM3, LAG3, and CTLA4 in CXCR5+CD8+ T cells and CXCR5−CD8+ T cells between HCs and HBV carriers. HCs: healthy controls (n = 23), HBV: hepatitis B virus carriers (n = 31); data are presented as the means ± SEs; *P < 0.05 and **P < 0.01