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Table 1 Demographic and laboratory characteristics of the RA-CAD, pure RA, and HC groups

From: Reduction of peripheral regulatory T cells in active rheumatoid arthritis patients with coronary artery disease

 

RA-CAD (n = 54)

RA (n = 43)

HC (n = 43)

p value

Age (years)a

63.52 ± 9.35

60.74 ± 6.29

60.91 ± 3.63

0.093

Male/femaleb

25/29

19/24

18/25

0.909

BMIa

24.04 ± 3.56

22.75 ± 3.55

23.70 ± 3.69

0.222

Smoking: male/femaleb

18 (72.0%)/0

13 (68.4%)/0

9 (50.0%)/0

0.302

Disease duration (years)c

5.00 (0.50, 12.00)

5.00 (1.50, 11.00)

0.434

DAS28 scorec

8.41 (5.93, 13.61)

8.90 (4.98, 15.46)

0.847

ESR (mm/h)c

52.50 (27.00, 84.00)

43.00 (25.00, 72.00)

0.459

CRP (mg/L)c

14.95 (5.54, 57.78)

21.80 (6.48, 41.70)

0.988

WBC (*109/L)d

6.68 (5.34, 8.85)

6.90 (5.29, 7.50)

5.81 (5.12, 7.35)

0.152

LY (*109/L)d

1.54 (1.16, 1.93)

1.66 (1.31, 2.14)

1.89 (1.61, 2.20)

0.009

MO (*109/L)d

0.52 (0.39, 0.64)

0.53 (0.39, 0.59)

0.43 (0.34, 0.58)

0.303

PLT (*109/L)d

257.50 (202.75, 293.25)

256.00 (215.00, 330.00)

230.00 (198.00, 274.00)

0.068

TC (mmol/L)d

3.71 (3.11, 4.27)

3.81 (3.23, 4.87)

4.24 (3.61, 4.69)

0.063

TG (mmol/L)d

1.17 (0.91, 1.66)

1.07 (0.76, 1.54)

1.12 (0.89, 1.57)

0.414

HDL (mmol/L)d

1.04 (0.91, 1.27)

1.18 (1.05, 1.28)

1.24 (1.01, 1.37)

0.061

LDL (mmol/L)d

1.93 (1.55, 2.38)

2.28 (1.88, 2.89)

2.36 (2.02, 2.87)

0.005

ApoA1 (g/L)c

1.13 (0.97, 1.34)

1.14 (1.02, 1.23)

0.813

ApoB100 (g/L)c

0.70 (0.57, 0.88)

0.78 (0.57, 1.01)

0.369

RF (IU/mL)c

40.00 (20.00, 160.00)

80.00 (20.00, 300.00)

0.225

Anti-CCP (IU/mL)c

433.65 (149.10, 1058.23)

829.80 (73.80, 1600.00)

0.218

IgG (g/L)c

12.30 (10.55, 15.85)

12.80 (8.92, 16.00)

0.912

IgM (g/L)c

2.32 (1.63, 3.56)

3.14 (2.20, 3.95)

0.037

IgA (g/L)c

1.01 (0.63, 1.33)

1.25 (0.87, 1.82)

0.007

  1. ESR: Erythrocyte sedimentation rate; CRP: C-reactive protein; WBC: white blood cell; LY: lymphocyte; MO: monocyte; PLT: platelet; TC: total cholesterol; TG: triglyceride; HDL: high-density lipoprotein; LDL: low-density lipoprotein; ApoA1: apolipoprotein-A1; ApoB100: apolipoprotein-B100; RF: rheumatoid factor; Anti-CCP: antibodies to cyclic citrullinated peptides; Ig: immunoglobulin
  2. aData are mean ± SD and compared using the independent samples t-test
  3. bData are number (n)/percentage (%) and measured using the chi-square test
  4. cData are medians (Q25, Q75) and compared using the Mann–Whitney U test
  5. dData are medians (Q25, Q75) and compared using the Kruskal–Wallis test