Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.
Skip to main content
Fig. 5 | BMC Immunology

Fig. 5

From: Activation of Toll-like receptor 2 enhances peripheral and tumor-infiltrating CD8+ T cell cytotoxicity in patients with gastric cancer

Fig. 5

The influence of TLR2 activation on cytolytic function of peripheral and tumor-infiltrating CD8+ T cells from NC and GC patients. CD8+ T cells were purified from HLA-A2 restricted individuals, including NC (peripheral bloods, n = 6) and GC patients (peripheral bloods and tumor specimens, n = 17), and were stimulated with or without Pam3Csk4 for 12 h in the presence of anti-CD3/CD28. Cells were washed twice, and 105 of stimulated CD8+ T cells were cocultured in direct and indirect contact with 5 × 105 of AGS cells for 48 h. The percentage of AGS cell death in a direct contact coculture system and b indirect contact coculture system was calculated by measuring lactate dehydrogenase release in the supernatants. The columns indicated means, and the bars indicated standard deviation. Significances were determined by One-Way ANOVA, LSD-t test or paired t test

Back to article page

BMC Immunology

ISSN: 1471-2172

Contact us