Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.
Skip to main content
Fig. 5 | BMC Immunology

Fig. 5

From: Phenotypic and immune functional profiling of patients with suspected Mendelian Susceptibility to Mycobacterial Disease in South Africa

Fig. 5

Comparison of distribution of fold changes in pSTATs for controls (n = 10) and patients. A Fold change in pSTAT1, i.e. IFN-γ signalling, for controls and patients in various cell subsets. pSTAT1 was measured for both unstimulated and IFN-γ (100 ng/mL) stimulated PBMCs; B Fold change in pSTAT4, i.e. IL-12 signalling, for controls and patients in various cell subsets. pSTAT4 was measured on PHA pre-stimulated PBMCs that were then either left unstimulated or stimulated with IL-12 (100 ng/mL). There were no significant differences in cytokine signalling between the controls and the patient group, however, the patient results should rather be considered on a case-by-case manner due to the diversity in clinical presentation of the patients

Back to article page

BMC Immunology

ISSN: 1471-2172

Contact us