Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.
Skip to main content
Fig. 2 | BMC Immunology

Fig. 2

From: Phenotypic and immune functional profiling of patients with suspected Mendelian Susceptibility to Mycobacterial Disease in South Africa

Fig. 2

IFN-γR1 detection and IFN-γ signalling in CD14 + monocytes in control and suspected MSMD patients. PID01, who has a known mutation in IFNGR1 (c.818del4), had elevated levels of IFN-γR1 expression, but decreased levels of IFN-γ signalling (fold-change in pSTAT1 detection following stimulation with IFN-γ) compared to the controls. Other patients for whom variants have been identified in IFN-γR are also shown in the figure—these suspected MSMD patients showed varying degrees of IFN-γR1 expression and IFN-γ signalling

Back to article page

BMC Immunology

ISSN: 1471-2172

Contact us