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Table 3 Top over-represented pathways included in pathway analyses

From: Transcriptomics of type 2 diabetic and healthy human neutrophils

Pathway

p-value

p-value (FDR)

p-value (Bonferroni)

KEGG Pathways

 Sphingolipid metabolism

2.52E-04

0.02

0.02

 Ether lipid metabolism

0.004

0.14

0.28

 Phospholipase D signaling pathway

0.02

0.24

1

 Fc gamma R-mediated phagocytosis

0.02

0.24

1

 Glycerophospholipid metabolism

0.02

0.24

1

GO Biological Processes

 Ammonium ion metabolic process

9.30e-5

0.10

0.15

 Surfactant homeostasis

1.20e-4

0.10

0.20

GO Molecular Functions

 Sphingosine-1-phosphate-phosphatase activity

1.20e-4

0.03

0.03

GO Cellular Components

 Plasma membrane

2.00e-4

0.03

0.04

    Integral component of plasma membrane

4.80e-4

0.03

0.11

  1. Uncorrected p-value < 0.05 considered over-represented; Bonferroni or FDR-corrected p-value < 0.05 considered significant. FDR false discovery rate; KEGG Kyoto Encyclopedia of Genes and Genomes; GO Gene Ontology
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BMC Immunology

ISSN: 1471-2172

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