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Table 2 Differential expression analysis of top 50 miRNAs in HIV-positive (n = 12) versus HIV-negative (n = 8) subjects from the test cohort

From: Small RNA sequencing of extracellular vesicles identifies circulating miRNAs related to inflammation and oxidative stress in HIV patients

 

baseMean

Log2 FC

P value

P adj

hsa-miR-26a-5p

620

−0.106

0.8216

0.9831

hsa-miR-148a-3p

514.38

0.798

0.2256

0.6636

hsa-miR-21-5p*

493.5

−0.405

0.4709

0.981

hsa-let-7i-5p

318.91

−0.191

0.7614

0.9831

hsa-miR-122-5p*

288.3

0.953

0.4941

0.9831

hsa-miR-1-3p

243.23

0.662

0.6196

0.9831

hsa-let-7a-5p*

224.95

1.512

0.0699

0.3493

hsa-let-7f-5p

216.84

−1.594

0.1263

0.4859

hsa-miR-423-5p*

210.36

0.239

0.8054

0.9831

hsa-let-7b-5p

181.67

1.098

0.2963

0.7134

hsa-miR-126-3p

134.04

3.067

0.0056

0.1169

hsa-let-7 g-5p

113.18

−0.108

0.9161

0.9831

hsa-let-7c-5p

109.04

2.39

0.0466

0.259

hsa-miR-30d-5p

102.88

−1.677

0.2039

0.6371

hsa-miR-99a-5p

96.3

0.527

0.6449

0.9831

hsa-miR-92a-3p

86.99

0.779

0.4643

0.981

hsa-miR-10a-5p*

83

2.9

0.0213

0.1779

hsa-miR-100-5p

80.05

1.389

0.2811

0.7134

hsa-miR-22-3p

79.59

2.307

0.0898

0.3743

hsa-miR-143-3p

73.61

1.308

0.3139

0.7134

hsa-miR-486-5p

69.46

1.373

0.3024

0.7134

hsa-miR-1246

64.35

−2.662

0.0342

0.2441

hsa-miR-155-5p

64.01

−0.322

0.7998

0.9831

hsa-miR-151a-3p

59.85

−0.261

0.8725

0.9831

hsa-miR-7-5p

57.03

0.038

0.9751

0.9917

hsa-miR-99b-5p

51.54

−0.933

0.7672

0.9831

hsa-miR-27a-3p

50.45

1.684

0.1728

0.5761

hsa-miR-320a

50.4

0.352

0.811

0.9831

hsa-miR-30c-5p

49.92

−1.558

0.2631

0.7134

hsa-let-7d-5p

44.98

2.287

0.0391

0.2447

hsa-miR-101-3p

44.39

−0.6

0.674

0.9831

hsa-miR-192-5p

41.22

2.429

0.0795

0.3615

hsa-miR-222-3p

41.18

0.194

0.8841

0.9831

hsa-miR-199a-3p

40.5

0.08

0.9438

0.9831

hsa-miR-199b-3p

40.5

0.08

0.9438

0.9831

hsa-miR-10b-5p

34.17

0.197

0.8896

0.9831

hsa-miR-181a-5p

33.66

−5.884

1.59E-05

0.0008

hsa-miR-27b-3p*

31.04

2.583

0.0112

0.1169

hsa-miR-26b-5p

30.29

0.012

0.9917

0.9917

hsa-miR-378a-3p

29.32

3.691

0.0117

0.1169

hsa-miR-24-3p

28.94

1.696

0.1589

0.5674

hsa-miR-191-5p

28.19

−0.71

0.676

0.9831

hsa-miR-25-3p

25.4

0.235

0.8851

0.9831

hsa-miR-125a-5p

22.86

−4.3

0.0104

0.1169

hsa-miR-451a

22.8

0.443

0.7961

0.9831

hsa-miR-146a-5p*

22.33

0.856

0.5596

0.9831

hsa-miR-125b-5p*

14.62

−0.665

0.6723

0.9831

hsa-miR-218-5p

14.38

1.004

0.5147

0.9831

hsa-miR-423-3p

12.6

0.485

0.7753

0.9831

hsa-miR-30a-5p

10.24

−0.284

0.8542

0.9831

  1. * miRNAs selected for qRT-PCR validation are indicated with an asterisk. Significant raw p-values are in bold