Fig. 2

IL-1β induces phosphorylation of both ERK and p38 in FDC-like cells. The total and phosphorylated levels of ERK (a) and p38 (b) MAPKs were examined by immunoblotting before and at the indicated time points after culture of FDC-like cells in the presence of IL-1β (10 pg/ml). Representative immunoblots and statistical analysis data (mean ± SEM) of three (a) or two (b) independent experiments are depicted. An asterisk(s) indicates a significant difference (*, p < 0.05; **, p < 0.01; ***, p < 0.001)