Figure 3
Exon 2 splice variation between rodent and human Ltb genes. Human LTB possesses at the end of exon 2 a splice donor site (underlined) that is missing in rodent orthologs. Deer mouse and house mouse genes have an A at this position, while the rat has a 3 nt deletion. Although woodchuck gene has a GT at this position, it does not appear to have the surrounding consensus sequence to support splicing. For this reason, rodent LTβ are substantially larger than human.