Figure 2

Induction of hIL-1βP-driven luciferase expression in IL-1β-luc transgenic mice by LPS. Dorsal and ventral views of a representative mouse are depicted for male (A) and female (B) mice. The color overlay on the images represents the photons/sec/cm2/steradian (p/s/cm2/sr), as indicated by the color scale next to the images. (C) Quantification of luciferase activity (photons/sec) of the whole body with the LivingImage software. Data presented are group means of 3 mice ± standard errors.