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Figure 3 | BMC Immunology

Figure 3

From: Methylprednisolone inhibits interleukin-17 and interferon-gamma expression by both naive and primed T cells

Figure 3

The effect of MP on IL-17 and IFN-γ production in T lymphocytes. CD3+ cells and LNC were stimulated with anti-CD3 antibody and anti-CD28 antibody (both at 1 μg/ml) in the absence or presence of MP (10 ng/ml) for 24 (A, C) and 48 (B, D) hours, and cell culture supernatants analyzed for IL-17 (A, B) and IFN-γ (C, D). CD3- cells were stimulated with LPS (1 μg/ml) for 48 hours and cell culture supernatants analyzed for IL-6 (E). Results are presented as % of values obtained in the corresponding cultures without MP. *p < 0.05 represents statistically significant difference to the corresponding culture without MP.

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BMC Immunology

ISSN: 1471-2172

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