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Figure 4 | BMC Immunology

Figure 4

From: Coexpression of GM-CSF and antigen in DNA prime-adenoviral vector boost immunization enhances polyfunctional CD8+ T cell responses, whereas expression of GM-CSF antigen fusion protein induces autoimmunity

Figure 4

GM-OVA alters the humoral immune response. Mice were immunized as described in figure legend 3. Ovalbumin-specific IgG1 (A) and IgG2a (B) antibodies were determined by ELISA. Shown are the mean OD405 values with their SEM (n = 6) from the vaccinated animals. Immune sera were diluted 1 to 10 and 1 to 1000 for the determination of IgG2a and IgG1 antibody levels, respectively. Only statistically significant differences between immunization regimens expressing either ovalbumin or GM-OVA in the one-way ANOVA test are indicated.

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BMC Immunology

ISSN: 1471-2172

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